MedPage Today: Smoking is Strong PAD Risk Factor in African Americans

African Americans who smoke are at substantially increased risk for developing peripheral artery disease (PAD), with a dose-dependent association with subclinical disease, a Jackson Heart Study analysis showed.

After adjustment for covariates, current smokers had increased risk of ankle‐brachial index <1 (OR 2.2, 95% CI, 1.5-3.3), as well as increased risk of abdominal aortic (OR 8.4, 95% CI, 5.8-12.0) and aortoiliac calcium (OR 9.6, 95% CI, 6.7-13.7).

“After risk adjustment, current smokers had 2.2 times the likelihood of subclinical lower extremity PAD and >8 times the likelihood of a high aortic calcium burden,” Donald Clark III, MD, of the University of Mississippi Medical Center in Jackson, and colleagues reported.

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